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Use of a prolactin-Cre/ROSA-YFP transgenic mouse provides no evidence for lactotroph transdifferentiation after weaning, or increase in lactotroph/somatotroph proportion in lactation

In rats, a shift from somatotroph dominance to lactotroph dominance during pregnancy and lactation is well reported. Somatotroph to lactotroph transdifferentiation and increased lactotroph mitotic activity are believed to account for this and associated pituitary hypertrophy. A combination of cell d...

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Detalles Bibliográficos
Autores principales: Castrique, Emma, Fernandez-Fuente, Marta, Le Tissier, Paul, Herman, Andy, Levy, Andy
Formato: Texto
Lenguaje:English
Publicado: BioScientifica 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2837375/
https://www.ncbi.nlm.nih.gov/pubmed/20139144
http://dx.doi.org/10.1677/JOE-09-0414