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Use of a prolactin-Cre/ROSA-YFP transgenic mouse provides no evidence for lactotroph transdifferentiation after weaning, or increase in lactotroph/somatotroph proportion in lactation
In rats, a shift from somatotroph dominance to lactotroph dominance during pregnancy and lactation is well reported. Somatotroph to lactotroph transdifferentiation and increased lactotroph mitotic activity are believed to account for this and associated pituitary hypertrophy. A combination of cell d...
Autores principales: | Castrique, Emma, Fernandez-Fuente, Marta, Le Tissier, Paul, Herman, Andy, Levy, Andy |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioScientifica
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2837375/ https://www.ncbi.nlm.nih.gov/pubmed/20139144 http://dx.doi.org/10.1677/JOE-09-0414 |
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