Cross-Presentation of a Spread-Defective MCMV Is Sufficient to Prime the Majority of Virus-Specific CD8+ T Cells

CD8+ T cells can be primed by peptides derived from endogenous proteins (direct presentation), or exogenously acquired protein (cross-presentation). However, the relative ability of these two pathways to prime CD8+ T cells during a viral infection remains controversial. Cytomegaloviruses (CMVs) can...

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Detalles Bibliográficos
Autores principales: Snyder, Christopher M., Allan, Jane E., Bonnett, Elizabeth L., Doom, Carmen M., Hill, Ann B.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2837378/
https://www.ncbi.nlm.nih.gov/pubmed/20300633
http://dx.doi.org/10.1371/journal.pone.0009681

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2837378/
https://www.ncbi.nlm.nih.gov/pubmed/20300633
http://dx.doi.org/10.1371/journal.pone.0009681

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