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Cross-Presentation of a Spread-Defective MCMV Is Sufficient to Prime the Majority of Virus-Specific CD8+ T Cells

CD8+ T cells can be primed by peptides derived from endogenous proteins (direct presentation), or exogenously acquired protein (cross-presentation). However, the relative ability of these two pathways to prime CD8+ T cells during a viral infection remains controversial. Cytomegaloviruses (CMVs) can...

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Detalles Bibliográficos
Autores principales:	Snyder, Christopher M., Allan, Jane E., Bonnett, Elizabeth L., Doom, Carmen M., Hill, Ann B.
Formato:	Texto
Lenguaje:	English
Publicado:	Public Library of Science 2010
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2837378/ https://www.ncbi.nlm.nih.gov/pubmed/20300633 http://dx.doi.org/10.1371/journal.pone.0009681

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