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Effects of Transcriptional Pausing on Gene Expression Dynamics
Stochasticity in gene expression affects many cellular processes and is a source of phenotypic diversity between genetically identical individuals. Events in elongation, particularly RNA polymerase pausing, are a source of this noise. Since the rate and duration of pausing are sequence-dependent, th...
Autores principales: | , , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2837387/ https://www.ncbi.nlm.nih.gov/pubmed/20300642 http://dx.doi.org/10.1371/journal.pcbi.1000704 |