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Membrane Damage Elicits an Immunomodulatory Program in Staphylococcus aureus

The Staphylococcus aureus HrtAB system is a hemin-regulated ABC transporter composed of an ATPase (HrtA) and a permease (HrtB) that protect S. aureus against hemin toxicity. S. aureus strains lacking hrtA exhibit liver-specific hyper-virulence and upon hemin exposure over-express and secrete immunom...

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Detalles Bibliográficos
Autores principales: Attia, Ahmed S., Benson, Meredith A., Stauff, Devin L., Torres, Victor J., Skaar, Eric P.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2837406/
https://www.ncbi.nlm.nih.gov/pubmed/20300601
http://dx.doi.org/10.1371/journal.ppat.1000802