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YfiBNR Mediates Cyclic di-GMP Dependent Small Colony Variant Formation and Persistence in Pseudomonas aeruginosa

During long-term cystic fibrosis lung infections, Pseudomonas aeruginosa undergoes genetic adaptation resulting in progressively increased persistence and the generation of adaptive colony morphotypes. This includes small colony variants (SCVs), auto-aggregative, hyper-adherent cells whose appearanc...

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Detalles Bibliográficos
Autores principales: Malone, Jacob G., Jaeger, Tina, Spangler, Christian, Ritz, Daniel, Spang, Anne, Arrieumerlou, Cécile, Kaever, Volkhard, Landmann, Regine, Jenal, Urs
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2837407/
https://www.ncbi.nlm.nih.gov/pubmed/20300602
http://dx.doi.org/10.1371/journal.ppat.1000804