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Substrate Induced Population Shifts and Stochastic Gating in the PBCV-1 mRNA Capping Enzyme
[Image: see text] The 317 residue PBCV-1 mRNA capping enzyme catalyzes the second enzymatic reaction in the formation of an N-7-methyl-GMP cap on the 5′-end of the nascent mRNA. It is composed of two globular domains bound by a short flexible peptide linker, which have been shown to undergo opening...
| Autores principales: | , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
American Chemical Society
2009
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2837470/ https://www.ncbi.nlm.nih.gov/pubmed/19301911 http://dx.doi.org/10.1021/ja808064g |