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IE63-specific T-cell responses associate with control of subclinical varicella zoster virus reactivation in individuals with malignancies

BACKGROUND: Reactivation of the varicella zoster virus (VZV) is more common in patients with malignancies; however, the molecular and cellular mechanisms underlying this susceptibility are unclear. METHODS: Using ex vivo interferon-γ ELISpot assays, we set out to analyse VZV-specific immune response...

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Detalles Bibliográficos
Autores principales: Malavige, G N, Rohanachandra, L T, Jones, L, Crack, L, Perera, M, Fernando, N, Guruge, D, Ogg, G S
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2837573/
https://www.ncbi.nlm.nih.gov/pubmed/20087346
http://dx.doi.org/10.1038/sj.bjc.6605542