Cargando…

Immunity of replicating Mu to self-integration: a novel mechanism employing MuB protein

We describe a new immunity mechanism that protects actively replicating/transposing Mu from self-integration. We show that this mechanism is distinct from the established cis-immunity mechanism, which operates by removal of MuB protein from DNA adjacent to Mu ends. MuB normally promotes integration...

Descripción completa

Detalles Bibliográficos
Autores principales: Ge, Jun, Lou, Zheng, Harshey, Rasika M
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2837660/
https://www.ncbi.nlm.nih.gov/pubmed/20226074
http://dx.doi.org/10.1186/1759-8753-1-8