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Immunity of replicating Mu to self-integration: a novel mechanism employing MuB protein
We describe a new immunity mechanism that protects actively replicating/transposing Mu from self-integration. We show that this mechanism is distinct from the established cis-immunity mechanism, which operates by removal of MuB protein from DNA adjacent to Mu ends. MuB normally promotes integration...
Autores principales: | Ge, Jun, Lou, Zheng, Harshey, Rasika M |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2837660/ https://www.ncbi.nlm.nih.gov/pubmed/20226074 http://dx.doi.org/10.1186/1759-8753-1-8 |
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