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Bile Acid-Induced Arrhythmia Is Mediated by Muscarinic M(2) Receptors in Neonatal Rat Cardiomyocytes

BACKGROUND: Intrahepatic cholestasis of pregnancy (ICP) is a common disease affecting up to 5% of pregnancies and which can cause fetal arrhythmia and sudden intrauterine death. We previously demonstrated that bile acid taurocholate (TC), which is raised in the bloodstream of ICP, can acutely alter...

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Detalles Bibliográficos
Autores principales: Sheikh Abdul Kadir, Siti H., Miragoli, Michele, Abu-Hayyeh, Shadi, Moshkov, Alexey V., Xie, Qilian, Keitel, Verena, Nikolaev, Viacheslav O., Williamson, Catherine, Gorelik, Julia
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2837738/
https://www.ncbi.nlm.nih.gov/pubmed/20300620
http://dx.doi.org/10.1371/journal.pone.0009689