Cargando…
Bile Acid-Induced Arrhythmia Is Mediated by Muscarinic M(2) Receptors in Neonatal Rat Cardiomyocytes
BACKGROUND: Intrahepatic cholestasis of pregnancy (ICP) is a common disease affecting up to 5% of pregnancies and which can cause fetal arrhythmia and sudden intrauterine death. We previously demonstrated that bile acid taurocholate (TC), which is raised in the bloodstream of ICP, can acutely alter...
Autores principales: | Sheikh Abdul Kadir, Siti H., Miragoli, Michele, Abu-Hayyeh, Shadi, Moshkov, Alexey V., Xie, Qilian, Keitel, Verena, Nikolaev, Viacheslav O., Williamson, Catherine, Gorelik, Julia |
---|---|
Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2010
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2837738/ https://www.ncbi.nlm.nih.gov/pubmed/20300620 http://dx.doi.org/10.1371/journal.pone.0009689 |
Ejemplares similares
-
Embryonic stem cell-derived cardiomyocytes as a model to study fetal arrhythmia related to maternal disease
por: Kadir, Siti H Sheikh Abdul, et al.
Publicado: (2009) -
Bile acids and their respective conjugates elicit different responses in neonatal cardiomyocytes: role of Gi protein, muscarinic receptors and TGR5
por: Ibrahim, Effendi, et al.
Publicado: (2018) -
Scanning ion conductance microscopy: a convergent high-resolution technology for multi-parametric analysis of living cardiovascular cells
por: Miragoli, Michele, et al.
Publicado: (2011) -
Atrial Fibrillation and Fibrosis: Beyond the Cardiomyocyte Centric View
por: Miragoli, Michele, et al.
Publicado: (2015) -
LKB1 is required for hepatic bile acid transport and canalicular membrane integrity in mice
por: Woods, Angela, et al.
Publicado: (2011)