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DNA Methylation as a Biomarker for Cardiovascular Disease Risk

BACKGROUND: Elevated serum homocysteine is associated with an increased risk of cardiovascular disease (CVD). This may reflect a reduced systemic remethylation capacity, which would be expected to cause decreased genomic DNA methylation in peripheral blood leukocytes (PBL). METHODOLOGY/PRINCIPAL FIN...

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Detalles Bibliográficos
Autores principales: Kim, Myungjin, Long, Tiffany I., Arakawa, Kazuko, Wang, Renwei, Yu, Mimi C., Laird, Peter W.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2837739/
https://www.ncbi.nlm.nih.gov/pubmed/20300621
http://dx.doi.org/10.1371/journal.pone.0009692