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Hemodynamic Environments from Opposing Sides of Human Aortic Valve Leaflets Evoke Distinct Endothelial Phenotypes In Vitro

The regulation of valvular endothelial phenotypes by the hemodynamic environments of the human aortic valve is poorly understood. The nodular lesions of calcific aortic stenosis (CAS) develop predominantly beneath the aortic surface of the valve leaflets in the valvular fibrosa layer. However, the m...

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Detalles Bibliográficos
Autores principales: Weinberg, Eli J., Mack, Peter J., Schoen, Frederick J., García-Cardeña, Guillermo, Kaazempur Mofrad, Mohammad R.
Formato: Texto
Lenguaje:English
Publicado: Springer US 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2837826/
https://www.ncbi.nlm.nih.gov/pubmed/20107896
http://dx.doi.org/10.1007/s10558-009-9089-9