Tomatine Adjuvantation of Protective Immunity to a Major Pre-erythrocytic Vaccine Candidate of Malaria is Mediated via CD8(+) T Cell Release of IFN-γ

The glycoalkaloid tomatine, derived from the wild tomato, can act as a powerful adjuvant to elicit an antigen-specific cell-mediated immune response to the circumsporozoite (CS) protein, a major pre-erythrocytic stage malaria vaccine candidate antigen. Using a defined MHC-class-I-restricted CS epito...

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Detalles Bibliográficos
Autores principales: Heal, Karen G., Taylor-Robinson, Andrew W.
Formato: Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2010
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2837906/
https://www.ncbi.nlm.nih.gov/pubmed/20300588
http://dx.doi.org/10.1155/2010/834326

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2837906/
https://www.ncbi.nlm.nih.gov/pubmed/20300588
http://dx.doi.org/10.1155/2010/834326

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