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Tomatine Adjuvantation of Protective Immunity to a Major Pre-erythrocytic Vaccine Candidate of Malaria is Mediated via CD8(+) T Cell Release of IFN-γ
The glycoalkaloid tomatine, derived from the wild tomato, can act as a powerful adjuvant to elicit an antigen-specific cell-mediated immune response to the circumsporozoite (CS) protein, a major pre-erythrocytic stage malaria vaccine candidate antigen. Using a defined MHC-class-I-restricted CS epito...
| Autores principales: | , |
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| Formato: | Texto |
| Lenguaje: | English |
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Hindawi Publishing Corporation
2010
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2837906/ https://www.ncbi.nlm.nih.gov/pubmed/20300588 http://dx.doi.org/10.1155/2010/834326 |