Cargando…

Novel Enzymatic Function of DNA Polymerase ν in Translesion DNA Synthesis Past Major Groove DNA−Peptide and DNA−DNA Cross-Links

[Image: see text] DNA polymerase ν (POLN or pol ν) is a newly discovered A family polymerase that generates a high error rate when incorporating nucleotides opposite dG; its translesion DNA synthesis (TLS) capability has only been demonstrated for high fidelity replication bypass of thymine glycol l...

Descripción completa

Detalles Bibliográficos
Autores principales: Yamanaka, Kinrin, Minko, Irina G., Takata, Kei-ichi, Kolbanovskiy, Alexander, Kozekov, Ivan D., Wood, Richard D., Rizzo, Carmelo J., Lloyd, R. Stephen
Formato: Texto
Lenguaje:English
Publicado: American Chemical Society 2010
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2838406/
https://www.ncbi.nlm.nih.gov/pubmed/20102227
http://dx.doi.org/10.1021/tx900449u