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Novel Enzymatic Function of DNA Polymerase ν in Translesion DNA Synthesis Past Major Groove DNA−Peptide and DNA−DNA Cross-Links
[Image: see text] DNA polymerase ν (POLN or pol ν) is a newly discovered A family polymerase that generates a high error rate when incorporating nucleotides opposite dG; its translesion DNA synthesis (TLS) capability has only been demonstrated for high fidelity replication bypass of thymine glycol l...
Autores principales: | Yamanaka, Kinrin, Minko, Irina G., Takata, Kei-ichi, Kolbanovskiy, Alexander, Kozekov, Ivan D., Wood, Richard D., Rizzo, Carmelo J., Lloyd, R. Stephen |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
American Chemical Society
2010
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2838406/ https://www.ncbi.nlm.nih.gov/pubmed/20102227 http://dx.doi.org/10.1021/tx900449u |
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