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Targeting ligand-gated ion channels in neurology and psychiatry: is pharmacological promiscuity an obstacle or an opportunity?

BACKGROUND: The traditional emphasis on developing high specificity pharmaceuticals ("magic bullets") for the treatment of Neurological and Psychiatric disorders is being challenged by emerging pathophysiology concepts that view disease states as abnormal interactions within complex networ...

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Detalles Bibliográficos
Autores principales: Bianchi, Matt T, Botzolakis, Emmanuel J
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2838756/
https://www.ncbi.nlm.nih.gov/pubmed/20196850
http://dx.doi.org/10.1186/1471-2210-10-3