Cargando…
Targeting ligand-gated ion channels in neurology and psychiatry: is pharmacological promiscuity an obstacle or an opportunity?
BACKGROUND: The traditional emphasis on developing high specificity pharmaceuticals ("magic bullets") for the treatment of Neurological and Psychiatric disorders is being challenged by emerging pathophysiology concepts that view disease states as abnormal interactions within complex networ...
Autores principales: | Bianchi, Matt T, Botzolakis, Emmanuel J |
---|---|
Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2010
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2838756/ https://www.ncbi.nlm.nih.gov/pubmed/20196850 http://dx.doi.org/10.1186/1471-2210-10-3 |
Ejemplares similares
-
Molecular Mingling: Multimodal Predictions of Ligand Promiscuity in Pentameric Ligand-Gated Ion Channels
por: Koniuszewski, Filip, et al.
Publicado: (2022) -
The Concise Guide to Pharmacology 2013/14: Ligand-Gated Ion Channels
por: Alexander, Stephen PH, et al.
Publicado: (2013) -
The Concise Guide to PHARMACOLOGY 2015/16: Ligand‐gated ion
channels
por: Alexander, Stephen PH, et al.
Publicado: (2015) -
THE CONCISE GUIDE TO PHARMACOLOGY 2017/18: Ligand‐gated ion channels
por: Alexander, Stephen PH, et al.
Publicado: (2017) -
Pentameric Ligand-Gated Ion Channels as Pharmacological Targets Against Chronic Pain
por: Lara, César O., et al.
Publicado: (2020)