Aptamer Antagonists of Myelin-Derived Inhibitors Promote Axon Growth

Myelin of the adult central nervous system (CNS) is one of the major sources of inhibitors of axon regeneration following injury. The three known myelin-derived inhibitors (Nogo, MAG, and OMgp) bind with high affinity to the Nogo-66 receptor (NgR) on axons and limit neurite outgrowth. Here we show t...

Descripción completa

Detalles Bibliográficos
Autores principales: Wang, Yuxuan, Khaing, Zin Z., Li, Na, Hall, Brad, Schmidt, Christine E., Ellington, Andrew D.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2838799/
https://www.ncbi.nlm.nih.gov/pubmed/20300533
http://dx.doi.org/10.1371/journal.pone.0009726

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2838799/
https://www.ncbi.nlm.nih.gov/pubmed/20300533
http://dx.doi.org/10.1371/journal.pone.0009726

Ejemplares similares