Cargando…
Aptamer Antagonists of Myelin-Derived Inhibitors Promote Axon Growth
Myelin of the adult central nervous system (CNS) is one of the major sources of inhibitors of axon regeneration following injury. The three known myelin-derived inhibitors (Nogo, MAG, and OMgp) bind with high affinity to the Nogo-66 receptor (NgR) on axons and limit neurite outgrowth. Here we show t...
| Autores principales: | , , , , , |
|---|---|
| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2010
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2838799/ https://www.ncbi.nlm.nih.gov/pubmed/20300533 http://dx.doi.org/10.1371/journal.pone.0009726 |