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Optimization of DNA delivery by three classes of hybrid nanoparticle/DNA complexes

Plasmid DNA encoding a luciferase reporter gene was complexed with each of six different hybrid nanoparticles (NPs) synthesized from mixtures of poly (D, L-lactide-co-glycolide acid) (PLGA 50:50) and the cationic lipids DOTAP (1, 2-Dioleoyl-3-Trimethyammonium-Propane) or DC-Chol {3β-[N-(N', N&#...

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Detalles Bibliográficos
Autores principales: Zhong, Qiu, Chinta, Dakshina Murthy Devanga, Pamujula, Sarala, Wang, Haifan, Yao, Xin, Mandal, Tarun K, Luftig, Ronald B
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2838804/
https://www.ncbi.nlm.nih.gov/pubmed/20181278
http://dx.doi.org/10.1186/1477-3155-8-6