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Expression profiling of mouse embryonic fibroblasts with a deletion in the helicase domain of the Werner Syndrome gene homologue treated with hydrogen peroxide

BACKGROUND: Werner Syndrome (WS) is a rare disorder characterized by the premature onset of a number of age-related diseases. The gene responsible for WS encodes a DNA helicase/exonuclease protein believed to affect different aspects of transcription, replication, and/or DNA repair. In addition to g...

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Detalles Bibliográficos
Autores principales: Labbé, Adam, Turaga, Ramachander VN, Paquet, Éric R, Garand, Chantal, Lebel, Michel
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2838845/
https://www.ncbi.nlm.nih.gov/pubmed/20175907
http://dx.doi.org/10.1186/1471-2164-11-127