Genome-wide analysis of aberrant methylation in human breast cancer cells using methyl-DNA immunoprecipitation combined with high-throughput sequencing

BACKGROUND: Cancer cells undergo massive alterations to their DNA methylation patterns that result in aberrant gene expression and malignant phenotypes. However, the mechanisms that underlie methylome changes are not well understood nor is the genomic distribution of DNA methylation changes well cha...

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Detalles Bibliográficos
Autores principales: Ruike, Yoshinao, Imanaka, Yukako, Sato, Fumiaki, Shimizu, Kazuharu, Tsujimoto, Gozoh
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2838848/
https://www.ncbi.nlm.nih.gov/pubmed/20181289
http://dx.doi.org/10.1186/1471-2164-11-137

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2838848/
https://www.ncbi.nlm.nih.gov/pubmed/20181289
http://dx.doi.org/10.1186/1471-2164-11-137

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