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Constitutive activation of BMP signalling abrogates experimental metastasis of OVCA429 cells via reduced cell adhesion

BACKGROUND: Activation of bone morphogenetic protein (BMP)4 signalling in human ovarian cancer cells induces a number of phenotypic changes in vitro, including altered cell morphology, adhesion, motility and invasion, relative to normal human ovarian surface epithelial cells. From these in vitro ana...

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Detalles Bibliográficos
Autores principales: Shepherd, Trevor G, Mujoomdar, Michelle L, Nachtigal, Mark W
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2838885/
https://www.ncbi.nlm.nih.gov/pubmed/20187934
http://dx.doi.org/10.1186/1757-2215-3-5