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Constitutive activation of BMP signalling abrogates experimental metastasis of OVCA429 cells via reduced cell adhesion
BACKGROUND: Activation of bone morphogenetic protein (BMP)4 signalling in human ovarian cancer cells induces a number of phenotypic changes in vitro, including altered cell morphology, adhesion, motility and invasion, relative to normal human ovarian surface epithelial cells. From these in vitro ana...
Autores principales: | Shepherd, Trevor G, Mujoomdar, Michelle L, Nachtigal, Mark W |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2838885/ https://www.ncbi.nlm.nih.gov/pubmed/20187934 http://dx.doi.org/10.1186/1757-2215-3-5 |
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