IRF-1 transcriptionally up-regulates PUMA which mediates the mitochondrial apoptotic pathway in IRF-1 induced apoptosis in cancer cells

Interferon Regulatory Factor-1 (IRF-1) is a transcription factor which acts as a tumor suppressor and causes apoptosis in cancer cells. We evaluated IRF-1 induced apoptosis in gastric cancer cell lines. We established stable clones in AGS cells that have a tetracycline inducible IRF-1 expression sys...

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Detalles Bibliográficos
Autores principales: Gao, J, Senthil, M, Ren, B, Yan, J, Xing, Q, Yu, J, Zhang, L, Yim, JH
Formato: Texto
Lenguaje:English
Publicado: 2009
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2838929/
https://www.ncbi.nlm.nih.gov/pubmed/19851330
http://dx.doi.org/10.1038/cdd.2009.156

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2838929/
https://www.ncbi.nlm.nih.gov/pubmed/19851330
http://dx.doi.org/10.1038/cdd.2009.156

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