Naive tumor-specific CD4(+) T cells differentiated in vivo eradicate established melanoma

In vitro differentiated CD8(+) T cells have been the primary focus of immunotherapy of cancer with little focus on CD4(+) T cells. Immunotherapy involving in vitro differentiated T cells given after lymphodepleting regimens significantly augments antitumor immunity in animals and human patients with...

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Detalles Bibliográficos
Autores principales: Xie, Ying, Akpinarli, Akgül, Maris, Charles, Hipkiss, Edward L., Lane, Malcolm, Kwon, Eun-Kyung M., Muranski, Pawel, Restifo, Nicholas P., Antony, Paul Andrew
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2010
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2839147/
https://www.ncbi.nlm.nih.gov/pubmed/20156973
http://dx.doi.org/10.1084/jem.20091921

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2839147/
https://www.ncbi.nlm.nih.gov/pubmed/20156973
http://dx.doi.org/10.1084/jem.20091921

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