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Naive tumor-specific CD4(+) T cells differentiated in vivo eradicate established melanoma
In vitro differentiated CD8(+) T cells have been the primary focus of immunotherapy of cancer with little focus on CD4(+) T cells. Immunotherapy involving in vitro differentiated T cells given after lymphodepleting regimens significantly augments antitumor immunity in animals and human patients with...
Autores principales: | Xie, Ying, Akpinarli, Akgül, Maris, Charles, Hipkiss, Edward L., Lane, Malcolm, Kwon, Eun-Kyung M., Muranski, Pawel, Restifo, Nicholas P., Antony, Paul Andrew |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2839147/ https://www.ncbi.nlm.nih.gov/pubmed/20156973 http://dx.doi.org/10.1084/jem.20091921 |
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