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IL-15 trans-presentation by pulmonary dendritic cells promotes effector CD8 T cell survival during influenza virus infection

We have recently demonstrated that peripheral CD8 T cells require two separate activation hits to accumulate to high numbers in the lungs after influenza virus infection: a primary interaction with mature, antigen-bearing dendritic cells (DCs) in the lymph node, and a second, previously unrecognized...

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Detalles Bibliográficos
Autores principales: McGill, Jodi, Van Rooijen, Nico, Legge, Kevin L.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2839152/
https://www.ncbi.nlm.nih.gov/pubmed/20212069
http://dx.doi.org/10.1084/jem.20091711