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Complete Genetic Correction of iPS Cells From Duchenne Muscular Dystrophy
Human artificial chromosome (HAC) has several advantages as a gene therapy vector, including stable episomal maintenance that avoids insertional mutations and the ability to carry large gene inserts including the regulatory elements. Induced pluripotent stem (iPS) cells have great potential for gene...
Autores principales: | , , , , , , , , , , , , , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2009
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2839293/ https://www.ncbi.nlm.nih.gov/pubmed/19997091 http://dx.doi.org/10.1038/mt.2009.274 |