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Widespread Transcriptional Autosomal Dosage Compensation in Drosophila Correlates with Gene Expression Level

Little is known about dosage compensation in autosomal genes. Transcription-level compensation of deletions and other loss-of-function mutations may be a mechanism of dominance of wild-type alleles, a ubiquitous phenomenon whose nature has been a subject of a long debate. We measured gene expression...

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Detalles Bibliográficos
Autores principales: McAnally, Ashley A., Yampolsky, Lev Y.
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2839349/
https://www.ncbi.nlm.nih.gov/pubmed/20333221
http://dx.doi.org/10.1093/gbe/evp054