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DNA Double Strand Break Repair and its Association with Inherited Predispositions to Breast Cancer

Mutations in BRCA1 account for the majority of familial aggregations of early onset breast and ovarian cancer (~70%) and about 1/5 of all early onset breast cancer families; in contrast, mutations in BRCA2 account for a smaller proportion of breast/ovarian cancer families and a similar proportion of...

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Detalles Bibliográficos
Autor principal: Scott, Rodney J
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2004
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2839992/
https://www.ncbi.nlm.nih.gov/pubmed/20233482
http://dx.doi.org/10.1186/1897-4287-2-1-37