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DNA Double Strand Break Repair and its Association with Inherited Predispositions to Breast Cancer
Mutations in BRCA1 account for the majority of familial aggregations of early onset breast and ovarian cancer (~70%) and about 1/5 of all early onset breast cancer families; in contrast, mutations in BRCA2 account for a smaller proportion of breast/ovarian cancer families and a similar proportion of...
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| Formato: | Texto |
| Lenguaje: | English |
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BioMed Central
2004
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2839992/ https://www.ncbi.nlm.nih.gov/pubmed/20233482 http://dx.doi.org/10.1186/1897-4287-2-1-37 |