Germline Missense Changes in the APC Gene and Their Relationship to Disease

Familial adenomatous polyposis (FAP) is characterized by the presence of hundreds to thousands of adenomas that carpet the entire colon and rectum. Nonsense and frameshift mutations in the adenomatous polyposis coli (APC) gene account for the majority of mutations identified to date and predispose p...

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Detalles Bibliográficos
Autores principales: Scott, Rodney J, Crooks, Renee, Rose, Lindy, Attia, John, Thakkinstian, Ammarin, Thomas, Lesley, Spigelman, Allan D, Meldrum, Cliff J
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2004
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2839999/
https://www.ncbi.nlm.nih.gov/pubmed/20233475
http://dx.doi.org/10.1186/1897-4287-2-2-81

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2839999/
https://www.ncbi.nlm.nih.gov/pubmed/20233475
http://dx.doi.org/10.1186/1897-4287-2-2-81

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