Cargando…

Economic and Practical Factors in Diagnosing HNPCC Using Clinical Criteria, Immunohistochemistry and Microsatellite Instability Analysis

AIM: To determine a cost-efficient strategy for HNPCC molecular diagnostic testing. METHODS: 138 families referred to a Regional Genetics Service had hMLH1 and hMSH2 mutation analysis. The sensitivity and specificity of clinical selection criteria with or without immunohistochemistry (IHC) and micro...

Descripción completa

Detalles Bibliográficos
Autores principales:	Pigatto, Francesca, Bateman, Adrian, Bunyan, David, Strike, Paul, Wilkins, Esta, Curtis, Claire, Duncan, Philippa, May, Denzil, Nugent, Karen, Eccles, Diana
Formato:	Texto
Lenguaje:	English
Publicado:	BioMed Central 2004
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2840004/ https://www.ncbi.nlm.nih.gov/pubmed/20233461 http://dx.doi.org/10.1186/1897-4287-2-4-175

Ejemplares similares

Lynch Syndrome (HNPCC) and Microsatellite Instability
por: Umar, Asad
Publicado: (2004)

Nuclear Pedigree Criteria of Suspected HNPCC
por: Kładny, Józef, et al.
Publicado: (2003)

Gene expression signatures for colorectal cancer microsatellite status and HNPCC
por: Kruhøffer, M, et al.
Publicado: (2005)

Usefulness of Immunohistochemistry for Microsatellite Instability Screening in Gastric Cancer
por: Bae, Yoon Sung, et al.
Publicado: (2015)

Lynch syndrome (HNPCC)
por: Kładny, Józef, et al.
Publicado: (2008)

Mutations Associated with HNPCC Predisposition — Update of ICG-HNPCC/INSiGHT Mutation Database
por: Peltomäki, Päivi, et al.
Publicado: (2004)

Microsatellite Instability in Endometrial Carcinoma by Immunohistochemistry, Association with Clinical and Histopathologic Parameters
por: Hashmi, Atif Ali, et al.
Publicado: (2019)

Atypical identification of Lynch syndrome by immunohistochemistry and microsatellite instability analysis on jejunal adenocarcinoma
por: McIlvried, Dawn E, et al.
Publicado: (2011)

Comparison of microsatellite instability detection by immunohistochemistry and molecular techniques in colorectal and endometrial cancer
por: Dedeurwaerdere, Franceska, et al.
Publicado: (2021)

Comprehensive Study of Microsatellite Instability Testing and Its Comparison With Immunohistochemistry in Gastric Cancers
por: Park, Yujun, et al.
Publicado: (2023)

HNPCC: Six new pathogenic mutations
por: Kunstmann, Erdmute, et al.
Publicado: (2004)

Deletion Mutations in an Australian Series of HNPCC Patients
por: McPhillips, Mary, et al.
Publicado: (2005)

The Association of the COMT V158M Polymorphism with Endometrial/Ovarian Cancer in HNPCC Families Adhering to the Amsterdam Criteria
por: Ashton, Katie A, et al.
Publicado: (2006)

Characterizing Microsatellite Instability and Chromosome Instability in Interval Colorectal Cancers
por: Cisyk, Amy L., et al.
Publicado: (2018)

HNPCC versus sporadic microsatellite-unstable colon cancers follow different routes toward loss of HLA class I expression
por: Dierssen, Jan Willem F, et al.
Publicado: (2007)

Reflex microsatellite instability & immunohistochemistry testing practices & follow-up of abnormal results at U.S. cancer programs
por: Beamer, Laura C, et al.
Publicado: (2011)

A retrospective study of consistency between immunohistochemistry and polymerase chain reaction of microsatellite instability in endometrial cancer
por: Wang, Cheng, et al.
Publicado: (2023)

Identification of HNPCC by Molecular Analysis of Colorectal and Endometrial Tumors
por: Vasen, H. F. A., et al.
Publicado: (2004)

Management of ovarian and endometrial cancers in women belonging to HNPCC carrier families: review of the literature and results of cancer risk assessment in Polish HNPCC families
por: Dębniak, Tadeusz, et al.
Publicado: (2015)

Editorial: Microsatellite and microsatellite instability
por: How-Kit, Alexandre, et al.
Publicado: (2023)

Utilizing microsatellite instability and immunohistochemistry to clinically interpret a novel germline mismatch repair mutation of uncertain significance
por: Ducaine, Whitney L, et al.
Publicado: (2011)

Diagnostic Performance of Immunohistochemistry Compared to Molecular Techniques for Microsatellite Instability and p53 Mutation Detection in Endometrial Cancer
por: Streel, Sylvie, et al.
Publicado: (2023)

Disease-causing gene-flanking genomic rearrangements in HNPCC patients
por: Morak, Monika, et al.
Publicado: (2011)

Retrospective analysis of patients with hereditary nonpolyposis colorectal cancer (HNPCC)
por: Zbigniew, Banaszkiewicz, et al.
Publicado: (2015)

MSI-Testing in Hereditary Non-Polyposis Colorectal Carcinoma (HNPCC)
por: Müller, Annegret, et al.
Publicado: (2004)

High predictability for identifying Lynch syndrome via microsatellite instability testing or immunohistochemistry in all Lynch-associated tumor types
por: Carethers, John M.
Publicado: (2019)

Investigation on the role of nsSNPs in HNPCC genes – a bioinformatics approach
por: Doss, C George Priya, et al.
Publicado: (2009)

Clinicopathological and genetic features of Chinese hereditary nonpolyposis colorectal cancer (HNPCC)
por: Liu, Fangqi, et al.
Publicado: (2014)

Concordance between microsatellite instability testing and immunohistochemistry for mismatch repair proteins and efficient screening of mismatch repair deficient gastric cancer
por: Yamamoto, Gou, et al.
Publicado: (2023)

Survey of HNPCC Management Analysis of Responses from 18 International Cancer Centres
por: Chow, Elizabeth, et al.
Publicado: (2005)

MUTYH Mutations Do Not Cause HNPCC or Late Onset Familial Colorectal Cancer
por: Stormorken, Astrid, et al.
Publicado: (2006)

HNPCC (Lynch Syndrome): Differential Diagnosis, Molecular Genetics and Management - a Review
por: Lynch, Henry T, et al.
Publicado: (2003)

The Norwegian PMS2 founder mutation c.989-1G > T shows high penetrance of microsatellite instable cancers with normal immunohistochemistry
por: Grindedal, Eli Marie, et al.
Publicado: (2014)

Minisatellite instability is found in colorectal tumours with mismatch repair deficiency
por: Coleman, M G, et al.
Publicado: (2001)

Microsatellite instability in ovarian neoplasms.
por: King, B. L., et al.
Publicado: (1995)

Microsatellite instability in colorectal cancer
por: Horvat, Matej, et al.
Publicado: (2011)

Microsatellite instability in colorectal cancer
por: Nojadeh, Jafar Nouri, et al.
Publicado: (2018)

Microsatellite instability in colorectal cancer
por: Gian, Luigi de’Angelis, et al.
Publicado: (2018)

Diagnostic microarray test for a genetic predisposition to hereditary nonpolyposis colorectal cancer (HNPCC)
por: Kaszuba, M, et al.
Publicado: (2012)

MSI Test to Distinguish between HNPCC and Other Predisposing Syndromes – of Value in Tailored Surveillance
por: Liljegren, Annelie, et al.
Publicado: (2004)

Cannot write session to /tmp/vufind_sessions/sess_ep0updc117g93ihrf3pvnm94v9