Discovery of Fragment Molecules That Bind the Human Peroxiredoxin 5 Active Site

The search for protein ligands is a crucial step in the inhibitor design process. Fragment screening represents an interesting method to rapidly find lead molecules, as it enables the exploration of a larger portion of the chemical space with a smaller number of compounds as compared to screening ba...

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Detalles Bibliográficos
Autores principales: Barelier, Sarah, Linard, Dominique, Pons, Julien, Clippe, André, Knoops, Bernard, Lancelin, Jean-Marc, Krimm, Isabelle
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2840032/
https://www.ncbi.nlm.nih.gov/pubmed/20305821
http://dx.doi.org/10.1371/journal.pone.0009744

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2840032/
https://www.ncbi.nlm.nih.gov/pubmed/20305821
http://dx.doi.org/10.1371/journal.pone.0009744

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