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Discovery of Fragment Molecules That Bind the Human Peroxiredoxin 5 Active Site
The search for protein ligands is a crucial step in the inhibitor design process. Fragment screening represents an interesting method to rapidly find lead molecules, as it enables the exploration of a larger portion of the chemical space with a smaller number of compounds as compared to screening ba...
| Autores principales: | , , , , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2010
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2840032/ https://www.ncbi.nlm.nih.gov/pubmed/20305821 http://dx.doi.org/10.1371/journal.pone.0009744 |