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ICAM-1 Clustering on Endothelial Cells Recruits VCAM-1

In the initial stages of transendothelial migration, leukocytes use the endothelial integrin ligands ICAM-1 and VCAM-1 for strong adhesion. Upon adhesion of the leukocyte to endothelial ICAM-1, ICAM-1 is clustered and recruited to the adhered leukocyte, promoting strong adhesion. In this study, we p...

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Detalles Bibliográficos
Autores principales: van Buul, Jaap D., van Rijssel, Jos, van Alphen, Floris P. J., van Stalborch, Anna-Marieke, Mul, Erik P. J., Hordijk, Peter L.
Formato: Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2840377/
https://www.ncbi.nlm.nih.gov/pubmed/20300427
http://dx.doi.org/10.1155/2010/120328