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Endonuclease IV Is the Main Base Excision Repair Enzyme Involved in DNA Damage Induced by UVA Radiation and Stannous Chloride

Stannous chloride (SnCl(2)) and UVA induce DNA lesions through ROS. The aim of this work was to study the toxicity induced by UVA preillumination, followed by SnCl(2) treatment. E. coli BER mutants were used to identify genes which could play a role in DNA lesion repair generated by these agents. Th...

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Detalles Bibliográficos
Autores principales: Motta, Ellen S., Souza-Santos, Paulo Thiago, Cassiano, Tuany R., Dantas, Flávio J. S., Caldeira-de-Araujo, Adriano, De Mattos, José Carlos P.
Formato: Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2840410/
https://www.ncbi.nlm.nih.gov/pubmed/20300433
http://dx.doi.org/10.1155/2010/376218