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KRAS Mutation in Colon Cancer: A Marker of Resistance to EGFR-I Therapy

INTRODUCTION AND DESIGN: The introduction of the epidermal growth factor receptor inhibitors (EGFR-I) has increased the treatment options available for patients with metastatic colorectal cancer (mCRC). Two EGFR-I agents currently approved for the treatment of mCRC are the fully human monoclonal ant...

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Detalles Bibliográficos
Autores principales: Siddiqui, Ahmad D., Piperdi, Bilal
Formato: Texto
Lenguaje:English
Publicado: Springer-Verlag 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2840670/
https://www.ncbi.nlm.nih.gov/pubmed/19936839
http://dx.doi.org/10.1245/s10434-009-0811-z