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Single-Vesicle Fusion Assay Reveals Munc18-1 Binding to the SNARE Core Is Sufficient for Stimulating Membrane Fusion

[Image: see text] Munc18, an essential regulatory protein for intracellular membrane fusion mediated by SNAREs, is known for stabilizing the closed conformation of syntaxin through the interaction with the N-terminal Habc domain (amino acids 28−146) of syntaxin. In addition, Munc18 accelerates membr...

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Detalles Bibliográficos
Autores principales: Diao, Jiajie, Su, Zengliu, Lu, Xiaobing, Yoon, Tae-Young, Shin, Yeon-Kyun, Ha, Taekjip
Formato: Texto
Lenguaje:English
Publicado: American Chemical Society 2010
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2841011/
https://www.ncbi.nlm.nih.gov/pubmed/20300453
http://dx.doi.org/10.1021/cn900034p