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Replacing the wild type loxP site in BACs from the public domain with lox66 using a lox66 transposon
BACKGROUND: Chromatin adjoining the site of integration of a transgene affects expression and renders comparisons of closely related transgenes, such as those derived from a BAC deletion series retrofitted with enhancer-traps, unreliable. Gene targeting to a pre-determined site on the chromosome is...
Autores principales: | , , , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2841073/ https://www.ncbi.nlm.nih.gov/pubmed/20170521 http://dx.doi.org/10.1186/1756-0500-3-38 |