Reduction of β-amyloid pathology by celastrol in a transgenic mouse model of Alzheimer's disease

BACKGROUND: Aβ deposits represent a neuropathological hallmark of Alzheimer's disease (AD). Both soluble and insoluble Aβ species are considered to be responsible for initiating the pathological cascade that eventually leads to AD. Therefore, the identification of therapeutic approaches that ca...

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Detalles Bibliográficos
Autores principales: Paris, Daniel, Ganey, Nowell J, Laporte, Vincent, Patel, Nikunj S, Beaulieu-Abdelahad, David, Bachmeier, Corbin, March, Amelia, Ait-Ghezala, Ghania, Mullan, Michael J
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2841120/
https://www.ncbi.nlm.nih.gov/pubmed/20211007
http://dx.doi.org/10.1186/1742-2094-7-17

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2841120/
https://www.ncbi.nlm.nih.gov/pubmed/20211007
http://dx.doi.org/10.1186/1742-2094-7-17

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