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The AP-1 repressor protein, JDP2, potentiates hepatocellular carcinoma in mice

BACKGROUND: The AP-1 transcription factor plays a major role in cell proliferation, apoptosis, differentiation and developmental processes. AP-1 proteins are primarily considered to be oncogenic. Gene disruption studies placed c-Jun as an oncogene at the early stage of a mouse model of hepatocellula...

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Detalles Bibliográficos
Autores principales: Bitton-Worms, Keren, Pikarsky, Eli, Aronheim, Ami
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2841123/
https://www.ncbi.nlm.nih.gov/pubmed/20214788
http://dx.doi.org/10.1186/1476-4598-9-54