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The AP-1 repressor protein, JDP2, potentiates hepatocellular carcinoma in mice
BACKGROUND: The AP-1 transcription factor plays a major role in cell proliferation, apoptosis, differentiation and developmental processes. AP-1 proteins are primarily considered to be oncogenic. Gene disruption studies placed c-Jun as an oncogene at the early stage of a mouse model of hepatocellula...
Autores principales: | Bitton-Worms, Keren, Pikarsky, Eli, Aronheim, Ami |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2841123/ https://www.ncbi.nlm.nih.gov/pubmed/20214788 http://dx.doi.org/10.1186/1476-4598-9-54 |
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