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Protection of p53 wild type cells from taxol by nutlin-3 in the combined lung cancer treatment
BACKGROUND: Mutations within the tumor suppressor TP53 gene are one of the most common genetic alterations present at high frequency in human tumors and have been shown to be associated with resistance to radio-chemotherapy. The lack of the wild type TP53 gene in cancer cells could be exploited for...
| Autores principales: | , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2010
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2841137/ https://www.ncbi.nlm.nih.gov/pubmed/20178585 http://dx.doi.org/10.1186/1471-2407-10-57 |