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Multimodal therapy for synergic inhibition of tumour cell invasion and tumour-induced angiogenesis

BACKGROUND: Squamous cell carcinoma of the head and neck (SCCHN) are highly invasive tumours with frequent local and distant recurrence. Metastasis formation requires degradation of the extracellular matrix, which is fulfilled by membrane-associated proteases such as the urokinase plasminogen activa...

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Detalles Bibliográficos
Autores principales: Zengel, Pamela, Ramp, Diana, Mack, Brigitte, Zahler, Stefan, Berghaus, Alexander, Muehlenweg, Bernd, Gires, Olivier, Schmitz, Suna
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2841144/
https://www.ncbi.nlm.nih.gov/pubmed/20222943
http://dx.doi.org/10.1186/1471-2407-10-92